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International Journal of Forensic Medicine

2023, Vol. 5, Issue 1, Part A

The biological clock genes in farm animals: A Scoping review


Author(s): Mohammed Hasan Dakheel, Rusul Saleem Abd, AL-Sarai Tamarah M, Ahmed Deyaa Kuhdair and Wed Abbas Mohammed

Abstract: The biological clock is a 24-hour cycle that is influenced by light and darkness, which are key factors in determining whether one feels alert or sleepy. Typically, the biological clock regulates how the body works. It is a system that is heavily utilized during the evolution of living things in order to help them adapt to the cyclic succession of their environment. For instance, metabolic processes coordinated with the circadian clock enable animals to ramp up feeding-related functions and adapt to changes in day-night length. The circadian rhythm is crucial in mediating the timing of seasonal breeding and other annual physiological fluctuations that are controlled by length, in addition to ambient light and food accessibility. Today. In the field of livestock, where we purposefully manipulate the photoperiod for production and management, this is crucial. However, the effects on the environment and the health of animals are frequently disregarded. The circadian clock is based on a group of transcriptional regulators that interact with one another in negative feedback loops and is present in almost all animal cell types. The suprachiasmatic nucleus, which functions as the body's internal clock, primarily regulates the physiological rhythm.SCN, or suprachiasmatic nucleus by continuing to cycle through periods of activity, rest, feeding, and fasting despite the absence of light. Many genes work together to accomplish this. One of the genes that produce proteins that can reversibly suppress the stimulation of the transcription of the Clock and BMAL1 genes in mammals is the cryptochrome (PER) gene (CRY). These play a crucial role in maintaining the circadian rhythm of mammals and enable the cycle to restart when the procedures are changed. While Jane studies retinoic acid receptor-related orphan receptors (RORs), Per and CRY REV-ERBs (REV-ERB) control BMAL1 gene transcription by controlling the BMAL1 gene's transcription. These genes work together to control mammals' biological clocks.

DOI: 10.33545/27074447.2023.v5.i1a.61

Pages: 25-27 | Views: 511 | Downloads: 241

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International Journal of Forensic Medicine
How to cite this article:
Mohammed Hasan Dakheel, Rusul Saleem Abd, AL-Sarai Tamarah M, Ahmed Deyaa Kuhdair, Wed Abbas Mohammed. The biological clock genes in farm animals: A Scoping review. Int J Forensic Med 2023;5(1):25-27. DOI: 10.33545/27074447.2023.v5.i1a.61
International Journal of Forensic Medicine

International Journal of Forensic Medicine

International Journal of Forensic Medicine
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